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The discoverer has worked in isolation.
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 The lone mad scientist Dr. Frankenstein with the monster in Bride of Frankenstein (1935).
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The image of a lone genius who struggles in secrecy in an attic laboratory and ends up making a revolutionary breakthrough is a staple of Hollywood's science-fiction films, but it is hard to find examples in real life. Scientific breakthroughs nowadays are almost always syntheses of the work of many scientists.
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